Roma use Jordan Veretout in a new advanced role amid an injury crisis as they host Radja Nainggolan’s Cagliari.
It kicks off at 14.00 UK time (13.00 GMT) at the Stadio Olimpico.
Follow all the build-up and action as it happens from today’s six Serie A gameson the LIVEBLOG.
The Giallorossi are dealing with an injury crisis that has ruled out Lorenzo Pellegrini, Henrikh Mkhitaryan, Alessandro Florenzi, Diego Perotti, Davide Zappacosta and Cengiz Under.
With Javier Pastore having already played on Thursday in the 1-1 Europa League draw away to Wolfsberg, it means Veretout is given a new role as the trequartista supporting Edin Dzeko, flanked by Nicolò Zaniolo and Justin Kluivert.
Cagliari have several former Roma players in the starting XI and it will be a very special game for Robin Olsen, Luca Pellegrini and of course Nainggolan.
They have more than a few injury problems too, missing Charalampos Lykogiannis, Alessio Cragno, Leonardo Pavoletti, Paolo Faragò, Ragnar Klavan and Simone Pinna.
Roma: Pau Lopez; Spinazzola, Mancini, Smalling, Kolarov; Cristante, Diawara; Zaniolo, Veretout, Kluivert; Dzeko
Cagliari:Olsen; Cacciatore, Pisacane, Ceppitelli, Lu Pellegrini; Nandez, Cigarini, Rog; Nainggolan; Joao Pedro, Simeone
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