Atalanta are forced to make changes with Papu Gomez and Luis Muriel leading the way against Fabio Quagliarella’s Sampdoria.
It kicks off at the Stadio Luigi Ferraris at 14.00 GMT.
You can follow all the build-up and action as it happens from today’s SIX Serie A gameson the LIVEBLOG.
Gian Piero Gasperini’s men are finding it difficult to balance their Champions League commitments with domestic affairs, but did get their first ever point in the tournament this week, holding Manchester City to a 1-1 draw.
That came just days after a 2-0 Serie A home defeat to Cagliari, which allowed the Sardinians and Lazio to catch them in joint fourth place.
Josip Ilicic was sent off for a reaction foul and he begins his two-match ban, with Duvan Zapata still out injured.
Ruslan Malinovskyi, Robin Gosens and Remo Freuler are not 100 per cent fit either.
Papu Gomez and former Sampdoria striker Muriel lead the attack, with Malinovskyi gritting his teeth to play on in the trequartista role.
Sampdoria are fresh off their first win under Claudio Ranieri, squeezing past SPAL in the final minutes, a result that allowed them to leave the foot of the table.
Last year’s Capocannoniere Fabio Quagliarella has support from Federico Bonazzoli rather than Manolo Gabbiadini.
It’s a special game for Emiliano Rigoni, who had six miserable months on loan with Atalanta last season before he was sent back to Zenit St Petersburg early.
Sampdoria:Audero; Bereszynski, Ferrari, Colley, Murru; Depaoli, Ekdal, Vieira, Jankto; Bonazzoli, Quagliarella
Atalanta:Gollini; Toloi, Palomino, Djimsiti; Hateboer, De Roon, Pasalic, Castagne; Malinovskyi; Gomez, Muriel
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